1. American Gangster: Nov. 2, 2007 ($43,565,115)
The biopic of Harlem gangster Frank Lucas stars Washington as the drug dealer who matches wits with Richie Roberts (Russell Crowe), the detective who helped bring him down. The film was directed and produced by Ridley Scott and written by Steve Zaillian. The opening weekend receipts came to $43,565,115, grossing $130,164,645 domestically and $266,500,000 worldwide.